September 13, 2024 Andrew Saik Chief Financial Officer and Treasurer Arvinas, Inc. 5 Science Park 395 Winchester Ave New Haven, Connecticut 06511 Re: Arvinas, Inc. Form 10-K for the fiscal year ended December 31, 2023 Filed February 27, 2024 File No. 001-38672 Dear Andrew Saik: We have completed our review of your filing. We remind you that the company and its management are responsible for the accuracy and adequacy of their disclosures, notwithstanding any review, comments, action or absence of action by the staff. Sincerely, Division of Corporation Finance Office of Life Sciences