October 7, 2019 Sean Cassidy Chief Financial Officer Arvinas, Inc. 5 Science Park 395 Winchester Avenue New Haven, Connecticut 06511 Re: Arvinas, Inc. Registration Statement on Form S-3 Filed October 1, 2019 File No. 333-234031 Dear Mr. Cassidy: This is to advise you that we have not reviewed and will not review your registration statement. Please refer to Rules 460 and 461 regarding requests for acceleration. We remind you that the company and its management are responsible for the accuracy and adequacy of their disclosures, notwithstanding any review, comments, action or absence of action by the staff. Please contact Gregory Dundas, Attorney Adviser, at (202) 551-3436 with any questions. Sincerely, Division of Corporation Finance Office of Life Sciences cc: Brian Johnson