Summary of Significant Accounting Policies Significant Accounting Policies [Text Block] Statistical Measurement [Domain] Statistical Measurement [Domain] Cash paid for amounts included in the measurement of lease liabilities: Cash Paid For Amounts Included In Measurement Of Lease Liabilities [Abstract] Cash paid for amounts included in the measurement of lease liabilities. Schedule of Available-for-Sale Marketable Securities Debt Securities, Available-for-Sale [Table Text Block] Restricted cash Restricted Cash, Current Award Timing Predetermined Award Timing Predetermined [Flag] Revenue, Remaining Performance Obligation, Expected Timing of Satisfaction, Start Date [Axis] Revenue, Remaining Performance Obligation, Expected Timing of Satisfaction, Start Date [Axis] Entity File Number Entity File Number Additional Paid-in Capital Additional Paid-in Capital [Member] Impairment of Long-Lived Assets Impairment or Disposal of Long-Lived Assets, Policy [Policy Text Block] Loss from equity method investment Loss from equity method investment Income (Loss) from Equity Method Investments Tabular List, Table Tabular List [Table Text Block] Leases [Abstract] Leases [Abstract] Updated Research Timelines Updated Research Timelines [Member] Updated Research Timelines New Accounting Pronouncements New Accounting Pronouncements, Policy [Policy Text Block] One-Time Cash Termination Fee One-Time Cash Termination Fee [Member] One-Time Cash Termination Fee Pledged Status [Axis] Pledged Status [Axis] Type of Restructuring [Domain] Type of Restructuring [Domain] Royalty payment Payments for Royalties Research and development tax credit Effective Income Tax Rate Reconciliation, Tax Credit, Research, Amount License License [Member] Gross Unrealized Losses Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Loss, before Tax Trading Arrangements, by Individual Trading Arrangements, by Individual [Table] Net loss per common share - basic (in dollars per share) Net loss per common share - basic (in usd per share) Earnings Per Share, Basic Adjustment to Compensation: Adjustment to Compensation [Axis] Named Executive Officers, Footnote Named Executive Officers, Footnote [Text Block] Accounts payable and accrued liabilities Increase (Decrease) in Accounts Payable and Accrued Liabilities Common stock reserved for issuance (in shares) Common Stock, Capital Shares Reserved for Future Issuance Income Statement And Statement Of Comprehensive Income [Abstract] Income Statement And Statement Of Comprehensive Income Stock compensation Deferred Tax Assets, Tax Deferred Expense, Compensation and Benefits, Share-Based Compensation Cost Total deferred income tax assets Deferred Tax Assets, Gross Schedule of Reportable Segment Financial Information Schedule of Segment Reporting Information, by Segment [Table Text Block] Common stock, shares issued (in shares) Stock Issued During Period, Shares, Employee Stock Purchase Plans Schedule of cash and cash equivalents Schedule of Cash and Cash Equivalents [Table Text Block] Total current Current Income Tax Expense (Benefit) Revenue, remaining performance obligation Revenue, Remaining Performance Obligation, Amount Adjustment to Compensation, Amount Adjustment to Compensation Amount Concentration risk, percentage Concentration Risk, Percentage Consolidation Consolidation, Policy [Policy Text Block] Stock-based compensation Share-Based Payment Arrangement, Noncash Expense Annual payment for license Annual License Fee Payment Annual license fee payment. Stock options Share-Based Payment Arrangement, Option [Member] Award Timing MNPI Disclosure Award Timing MNPI Disclosure [Text Block] Schedule Of Property Plant And Equipment [Table] Property, Plant and Equipment [Table] Research and Development Expenses Research and Development Expense, Policy [Policy Text Block] Cash and Cash Equivalents Cash and Cash Equivalents, Policy [Policy Text Block] Commitments And Contingencies [Table] Commitments And Contingencies [Table] Commitments and contingencies. Percent Effective Income Tax Rate Reconciliation, Percent [Abstract] Antidilutive Securities [Axis] Antidilutive Securities [Axis] Total stockholders' equity Beginning balance Ending balance Equity, Attributable to Parent Measurement Frequency [Axis] Measurement Frequency [Axis] Summary Of Significant Accounting Policies [Table] Summary Of Significant Accounting Policies [Table] Summary of significant of accounting policies. Insider Trading Policies and Procedures [Line Items] New York NEW YORK Compensation expense Share-Based Payment Arrangement, Expense Common stock, shares authorized (in shares) Common Stock, Shares Authorized Schedule of Property, Equipment and Leasehold Improvements Property, Plant and Equipment [Table Text Block] Common stock issued, net of issuance costs (in shares) Stock Issued During Period, Shares, New Issues Current assets: Assets, Current [Abstract] Forfeited (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Forfeitures in Period Total liabilities and stockholders' equity Liabilities and Equity Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items] Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items] Fair Value, Measurements, Recurring Fair Value, Recurring [Member] Options Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding [Roll Forward] Concentration Risk Benchmark [Axis] Concentration Risk Benchmark [Axis] Concentration of Credit Risk and Other Risks and Uncertainties Concentration Risk, Credit Risk, Policy [Policy Text Block] Sales-based Milestone Payments Sales Based Milestone Payments [Member] Sales-based milestone payments. Liabilities and stockholders' equity Liabilities and Equity [Abstract] US state and local   State and Local Jurisdiction [Member] Other income (expense) Other Nonoperating Income (Expense) [Abstract] Cover [Abstract] Cover [Abstract] Other Deferred Tax Assets, Other Future grant of incentive units to service providers, percentage Future Grant Of Incentive Units To Service Providers Percentage Future grant of incentive units to service providers, percentage. Maximum Maximum [Member] General and Administrative Expense General and Administrative Expense [Member] Vested and exercisable (in dollars per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Exercise Price Schedule Of Equity Method Investments [Table] Equity Method Investment [Table] Accounting Policies [Abstract] Accounting Policies [Abstract] Pennsylvania PENNSYLVANIA Proceeds from exercise of stock options and issuance of ESPP shares Proceeds From Exercise Of Stock Options And Issuance Of Employee Stock Shares Proceeds From Exercise Of Stock Options And Issuance Of Employee Stock Shares Schedule of Maturities of Operating Lease Liabilities Lessee, Operating Lease, Liability, to be Paid, Maturity [Table Text Block] Concentration Risk Type [Domain] Concentration Risk Type [Domain] Non-PEO NEO Average Total Compensation Amount Non-PEO NEO Average Total Compensation Amount Debt Instrument [Line Items] Debt Instrument [Line Items] Schedule Of Share Based Compensation Arrangements By Share Based Payment Award [Table] Schedule of Share-Based Compensation Arrangements by Share-Based Payment Award [Table] Treasury Treasury Stock, Common [Member] Total fair value of RSUs vested Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period, Fair Value Adjustment to Non-PEO NEO Compensation Footnote Adjustment to Non-PEO NEO Compensation Footnote [Text Block] Pay vs Performance Disclosure [Line Items] Class of Warrant or Right [Axis] Class of Warrant or Right [Axis] Total Operating Lease, Liability Additions Accounts Receivable, After Allowance For Credit Loss, Current, Additions Accounts Receivable, After Allowance For Credit Loss, Current, Additions Forgone Recovery due to Disqualification of Tax Benefits, Amount Forgone Recovery due to Disqualification of Tax Benefits, Amount Non-Rule 10b5-1 Arrangement Terminated Non-Rule 10b5-1 Arrangement Terminated [Flag] Depreciation and amortization Depreciation, Depletion and Amortization, Nonproduction Entity Shell Company Entity Shell Company Debt Instrument [Table] Schedule of Long-Term Debt Instruments [Table] Beginning balance Ending balance Accounts Payable, Contract Balances, Current Accounts Payable, Contract Balances, Current Proceeds from disposal of property, equipment and leasehold improvements Proceeds from Sale of Property, Plant, and Equipment Statement of Stockholders' Equity [Abstract] Statement of Stockholders' Equity [Abstract] Schedule of Income Tax Paid, Net of Refunds Schedule of Cash Flow, Supplemental Disclosures [Table Text Block] Oerth Oerth Bio Limited Liability Corporation [Member] Oerth Bio LLC. Less: current installments included within Accounts Payable and Accrued Liabilities Long-Term Debt, Current Maturities Statement of Cash Flows [Abstract] Statement of Cash Flows [Abstract] Company Selected Measure Amount Company Selected Measure Amount 2028 Lessee, Operating Lease, Liability, to be Paid, Year Three Award Timing MNPI Considered Award Timing MNPI Considered [Flag] Comprehensive loss Comprehensive Income (Loss), Net of Tax, Attributable to Parent Name Measure Name Restructuring accrual Restructuring Reserve Letter of Credit Letter of Credit [Member] Current portion of operating lease liability Operating Lease, Liability, Current Debt instrument interest payments term (in months) Debt Instrument Interest Payments Term Debt instrument interest payments term. Document Fiscal Period Focus Document Fiscal Period Focus Award Timing Method Award Timing Method [Text Block] Award Type [Axis] Award Type [Axis] Deferred revenue Contract with Customer, Liability, Noncurrent Total Long-Term Debt Development Milestone Payments Development Milestone Payments [Member] Development milestone payments. Legal Entity [Axis] Legal Entity [Axis] Total assets Assets Equity Distribution Agreement Equity Distribution Agreement [Member] Equity Distribution Agreement Investment, Name [Domain] Investment, Name [Domain] Equity-based Compensation Share-Based Payment Arrangement [Policy Text Block] Trading Symbol Trading Symbol 2029 Lessee, Operating Lease, Liability, to be Paid, Year Four Required milestone payments Required Milestone Payments Required Milestone Payments Restricted Cash Cash and Cash Equivalents, Restricted Cash and Cash Equivalents, Policy [Policy Text Block] Contract liabilities: Deferred revenue Change in Contract with Customer, Liability [Roll Forward] Change in Contract with Customer, Liability Geographical [Domain] Geographical [Domain] Changes in valuation allowance Effective Income Tax Rate Reconciliation, Change in Deferred Tax Assets Valuation Allowance, Percent Amortization Capitalized Contract Cost, Amortization During Period Capitalized Contract Cost, Amortization During Period Income Taxes Income Tax, Policy [Policy Text Block] Issuance of common stock under equity incentive plans (in shares) Shares Issued, Shares, Share-Based Payment Arrangement, after Forfeiture Entity Address, City or Town Entity Address, City or Town Debt securities Debt Securities Cash flows from operating activities: Cash Provided by (Used in) Operating Activity, Including Discontinued Operation [Abstract] Research and development tax credit Effective Income Tax Rate Reconciliation, Tax Credit, Research, Percent Other segment expense, net Segment Reporting, Other Segment Item, Amount Concentration Risk Type [Axis] Concentration Risk Type [Axis] Non-PEO NEO Average Compensation Actually Paid Amount Non-PEO NEO Average Compensation Actually Paid Amount Statement of Income Location, Balance [Domain] Statement of Income Location, Balance [Domain] RSUs Restricted Stock Units (RSUs) [Member] Compensation Actually Paid vs. Other Measure Compensation Actually Paid vs. Other Measure [Text Block] Contract Termination [Domain] Contract Termination [Domain] Contract Termination [Domain] Entity Emerging Growth Company Entity Emerging Growth Company 2028 Long-Term Debt, Maturity, Year Three Entity Common Stock Shares Outstanding Entity Common Stock, Shares Outstanding Right-of-use assets obtained in exchange for new lease obligations Right-of-Use Asset Obtained in Exchange for Operating Lease Liability Beginning balance (in shares) Ending balance (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Number Change in Fair Value as of Vesting Date of Prior Year Equity Awards Vested in Covered Year Change in Fair Value as of Vesting Date of Prior Year Equity Awards Vested in Covered Year [Member] Level 2 Fair Value, Inputs, Level 2 [Member] Document Financial Statement Error Correction Document Financial Statement Error Correction [Flag] State and local income taxes, net of federal income tax effect Effective Income Tax Rate Reconciliation, State and Local Income Taxes, Amount Equity method investments Equity Method Investments Insider Trading Policies and Procedures Not Adopted Insider Trading Policies and Procedures Not Adopted [Text Block] Common stock, shares outstanding (in shares) Beginning balance (in shares) Ending balance (in shares) Common Stock, Shares, Outstanding Asset Pledged as Collateral Asset Pledged as Collateral [Member] Piper Sandler and Cantor Piper Sandler And Cantor [Member] Piper sandler and cantor. 101 College Street LLC 101 College Street LLC [Member] 101 College Street LLC Schedule of Income Tax Expense Schedule of Components of Income Tax Expense (Benefit) [Table Text Block] Plan Name [Axis] Plan Name [Axis] Property, Equipment, and Leasehold Improvements Property, Plant and Equipment, Policy [Policy Text Block] Schedule of Supplemental Cash Flow Information Related to Leases Schedule Of Supplemental Cash Flow Information Related To Leases Table [Table Text Block] Supplemental cash flow information related to leases. PEO PEO [Member] Income Tax Disclosure [Line Items] Income Tax Disclosure [Line Items] Income tax disclosure. Employee Severance Employee Severance [Member] License, Second Licensed Product License, Second Licensed Product [Member] License, Second Licensed Product Other programs Other Programs [Member] Other Programs Contingent payments Revenue, Remaining Performance Obligation, Contingent Payments Revenue, Remaining Performance Obligation, Contingent Payments Interest income, net Interest income, net Investment Income, Interest Net loss before income taxes and loss from equity method investment Income (Loss) from Continuing Operations before Equity Method Investments, Income Taxes, Noncontrolling Interest Current: Current Income Tax Expense (Benefit), Continuing Operations [Abstract] Income Tax Paid, by Individual Jurisdiction [Line Items] Income Tax Paid, by Individual Jurisdiction [Line Items] (Decrease) increase in valuation allowance Valuation Allowance, Deferred Tax Asset, Increase (Decrease), Amount Income taxes Accrued Income Taxes, Current Changes in operating assets and liabilities: Adjustment to Reconcile Net Income to Cash Provided by (Used in) Operating Activity, Increase (Decrease) in Operating Capital [Abstract] Novartis Pharma AG Novartis Pharma AG [Member] Novartis Pharma AG Dividends or Other Earnings Paid on Equity Awards not Otherwise Reflected in Total Compensation for Covered Year Dividends or Other Earnings Paid on Equity Awards not Otherwise Reflected in Total Compensation for Covered Year [Member] Changes in valuation allowance Effective Income Tax Rate Reconciliation, Change in Deferred Tax Assets Valuation Allowance, Amount Property, equipment and leasehold improvements Deferred Tax Liabilities, Property, Plant and Equipment Accumulated Deficit Retained Earnings [Member] Prepaid expenses and other current assets Prepaid Expense and Other Assets, Current Income Tax Jurisdiction [Axis] Income Tax Jurisdiction [Axis] Shares Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Number of Shares [Roll Forward] Pledged Status [Domain] Pledged Status [Domain] Schedule of Components of Accounts Payable and Accrued Liabilities Schedule of Accrued Liabilities [Table Text Block] Entity Address, Postal Zip Code Entity Address, Postal Zip Code Restatement Determination Date Restatement Determination Date Share-based Payment Arrangement [Abstract] Share-Based Payment Arrangement [Abstract] Cash, cash equivalents and restricted cash, beginning of the period Cash, cash equivalents and restricted cash, end of the period Cash, cash equivalents and restricted cash Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Continuing Operation Consolidated Statements of Operations Income Statement [Abstract] Income tax expense Income tax expense Income tax expense Income tax expense Income Tax Expense (Benefit) Number of inducement grants (in shares) Share-Based Compensation Arrangement By Share-Based Payment Award, Equity Instruments Other Than Options, Inducement Grants Share-Based Compensation Arrangement By Share-Based Payment Award, Equity Instruments Other Than Options, Inducement Grants Purchase of marketable securities Payments to Acquire Marketable Securities Sale of Stock [Domain] Sale of Stock [Domain] Released (in shares) Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options, Released In Period Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options, Released In Period Collaboration agreement direct and incremental costs incurred Direct And Incremental Costs Incurred To Obtain The Contract Direct And Incremental Costs Incurred To Obtain The Contract Aggregate Intrinsic Value Aggregate Intrinsic Value [Abstract] Aggregate Intrinsic Value Annual increase in reserved shares of common stock (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Other Increases (Decreases) in Period Preferred stock, shares issued (in shares) Preferred Stock, Shares Issued Pension Adjustments Service Cost Pension Adjustments Service Cost [Member] Payments for collaboration Payments For Collaboration Payments For Collaboration Product and Service [Domain] Product and Service [Domain] Fair Value Hierarchy and NAV [Axis] Fair Value Hierarchy and NAV [Axis] Customer Concentration Risk Customer Concentration Risk [Member] Total property, equipment and leasehold improvements Property, Plant and Equipment, Gross Cash, cash equivalents, restricted cash and marketable securities Cash, Cash Equivalents, Restricted Cash and Marketable Securities Cash, Cash Equivalents, Restricted Cash and Marketable Securities Restatement does not require Recovery Restatement Does Not Require Recovery [Text Block] Pre-Funded Warrant Pre-Funded Warrant [Member] Pre-Funded Warrant Organization, Consolidation and Presentation of Financial Statements [Abstract] Organization, Consolidation and Presentation of Financial Statements [Abstract] Income Tax Paid, by Individual Jurisdiction [Table] Income Tax Paid, by Individual Jurisdiction [Table] Restructuring Activity Restructuring and Related Activities Disclosure [Text Block] Amortization of right-of-use assets Operating Lease, Right-of-Use Asset, Periodic Reduction Compensation Actually Paid vs. Company Selected Measure Compensation Actually Paid vs. Company Selected Measure [Text Block] City Area Code City Area Code Award Timing, How MNPI Considered Award Timing, How MNPI Considered [Text Block] US federal   Income Tax Paid, Federal, after Refund Received Payments received Proceeds from Collaborators All Trading Arrangements All Trading Arrangements [Member] Equity Awards Adjustments, Footnote Equity Awards Adjustments, Footnote [Text Block] Total Shareholder Return Vs Peer Group Total Shareholder Return Vs Peer Group [Text Block] Vested and expected to vest (in Years) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Weighted Average Remaining Contractual Term Program-specific external expense: Research And Development Expense, Program Specific Research And Development Expense, Program Specific Beginning balance (in shares) Ending balance (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Number Commitments and Contingencies Disclosure [Abstract] Commitments and Contingencies Disclosure [Abstract] Schedule of Contract Balances Contract with Customer, Contract Asset, Contract Liability, and Receivable [Table Text Block] Net deferred income tax liability Deferred Tax Liabilities, Net Cash flows from investing activities: Cash Provided by (Used in) Investing Activity, Including Discontinued Operation [Abstract] General and administrative General and administrative expense General and Administrative Expense Pay vs Performance Disclosure Pay vs Performance Disclosure [Table] Net cash used in operating activities Cash Provided by (Used in) Operating Activity, Including Discontinued Operation Equity Method Investments and Joint Ventures [Abstract] Equity Method Investments and Joint Ventures [Abstract] ARV-102 ARV-102 [Member] ARV-102 Property and equipment, estimated useful life Property, Plant and Equipment, Useful Life Preferred stock par value (in dollars per share) Preferred Stock, Par or Stated Value Per Share Schedule of Assumptions Used to Determine Fair Value of Stock Options Granted Schedule of Share-Based Payment Award, Stock Options, Valuation Assumptions [Table Text Block] Schedule Of Equity Method Investments [Line Items] Schedule of Equity Method Investments [Line Items] Equity Valuation Assumption Difference, Footnote Equity Valuation Assumption Difference, Footnote [Text Block] Schedule of Components of Lease Expense Lease, Cost [Table Text Block] PEO Total Compensation Amount PEO Total Compensation Amount Vested and expected to vest (in dollars per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Weighted Average Exercise Price Federal Deferred Federal Income Tax Expense (Benefit) Equity Components [Axis] Equity Components [Axis] Property Plant And Equipment [Line Items] Property, Plant and Equipment [Line Items] Unrecognized Tax Benefits [Roll Forward] Unrecognized Tax Benefits [Roll Forward] 2018 Assistance Agreement Two Thousand And Eighteen Assistance Agreement [Member] Two thousand and eighteen assistance agreement. Auditor Name Auditor Name Non-Rule 10b5-1 Arrangement Adopted Non-Rule 10b5-1 Arrangement Adopted [Flag] License, First Licensed Product License, First Licensed Product [Member] License, First Licensed Product Number of reportable segments Number of Reportable Segments Removal Of Combination Trials Removal Of Combination Trials [Member] Removal Of Combination Trials Supplemental disclosure of cash flow information: Supplemental Cash Flow Information [Abstract] Amortized Cost Debt Securities, Available-for-Sale, Amortized Cost Restructuring Cost and Reserve [Line Items] Restructuring Cost and Reserve [Line Items] Other Performance Measure, Amount Other Performance Measure, Amount Schedule of restrictions on cash and cash equivalents Restrictions on Cash and Cash Equivalents [Table Text Block] Entity Address, State or Province Entity Address, State or Province Marketable Securities Marketable Securities, Policy [Policy Text Block] Schedule Of Antidilutive Securities Excluded From Computation Of Earnings Per Share [Table] Antidilutive Security, Excluded EPS Calculation [Table] Fair Value Measurements Fair Value Measurement, Policy [Policy Text Block] Total current liabilities Liabilities, Current Amount Income Tax Expense (Benefit), Effective Income Tax Rate Reconciliation, Amount [Abstract] Reduction in workforce (as a percent) Restructuring and Related Cost, Number of Positions Eliminated, Period Percent Commercial Milestones Commercial Milestones [Member] Commercial milestones. Collaboration contract asset and other assets Collaboration Contract Asset And Other Assets Collaboration Contract Asset And Other Assets Accounts payable related to collaborations Change in Accounts Payable, after Allowance for Credit Loss [Roll Forward] Change in Accounts Payable, after Allowance for Credit Loss Individual: Individual [Axis] Reportable Segment Reportable Segment [Member] Reportable Segment Discretionary matching contributions Defined Contribution Plan, Cost Audit Information [Abstract] Audit Information Success-Based Milestone Payments Success-Based Milestone Payments [Member] Success-Based Milestone Payments Equity interest Equity Method Investment, Aggregate Cost Other receivables Increase (Decrease) in Other Receivables Income Tax Jurisdiction [Domain] Income Tax Jurisdiction [Domain] Document Annual Report Document Annual Report Research and Development Expense Research and Development Expense [Member] Change in Accounting Estimate by Type [Axis] Effect of Change in Accounting Estimate, Type [Axis] Entity [Domain] Entity [Domain] Net cash provided by investing activities Cash Provided by (Used in) Investing Activity, Including Discontinued Operation Revenue, remaining performance obligation, expected timing of satisfaction, period Revenue, Remaining Performance Obligation, Expected Timing of Satisfaction, Period Aggregate Change in Present Value of Accumulated Benefit for All Pension Plans Reported in Summary Compensation Table Aggregate Change in Present Value of Accumulated Benefit for All Pension Plans Reported in Summary Compensation Table [Member] Document Fiscal Year Focus Document Fiscal Year Focus Basis of Presentation Basis of Accounting, Policy [Policy Text Block] Operating lease right of use assets Operating Lease, Right-of-Use Asset Forgone Recovery, Explanation of Impracticability Forgone Recovery, Explanation of Impracticability [Text Block] 2018 Plan 2018 Plan Two Thousand Eighteen Stock Incentive Plan [Member] Two thousand eighteen stock incentive plan. Repayments of long-term debt Repayments of Long-Term Debt Capitalized research and development Deferred Tax Asset, In-Process Research and Development Effective tax rate Effective Income Tax Rate Reconciliation, Percent Entity Interactive Data Current Entity Interactive Data Current Operating lease cost Operating Lease, Cost Revenue recognized from balances not held at the beginning of the period Contract with Customer, Liability, Revenue Recognized From New Collaboration Contract with Customer, Liability, Revenue Recognized From New Collaboration Plan Name [Domain] Plan Name [Domain] Additions to collaboration agreements Contract With Customer, Liability, Increase (Decrease) For Additions To Collaboration Agreements Contract With Customer, Liability, Increase (Decrease) For Additions To Collaboration Agreements Compensation expense not yet recognized, period of recognition (in years) Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Period for Recognition Less valuation allowance Deferred Tax Assets, Valuation Allowance Deferred revenue Deferred Tax Assets, Deferred Income Revenue Recognition and Deferred Revenue Revenue from Contract with Customer [Policy Text Block] Vested and exercisable Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Intrinsic Value Stock compensation Effective Income Tax Rate Reconciliation, Nondeductible Expense, Share-Based Payment Arrangement, Amount Less: Segment Reconciliation [Abstract] Segment Information Segment Reporting Disclosure [Text Block] Vepdegestrant ARV-471 ARV-471 [Member] ARV-471 Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items] Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] Loss carryforwards Deferred Tax Assets, Operating Loss Carryforwards Federal Current Federal Tax Expense (Benefit) Long-Lived Tangible Asset [Axis] Long-Lived Tangible Asset [Axis] Increase (Decrease) in Stockholders' Equity [Roll Forward] Increase (Decrease) in Stockholders' Equity [Roll Forward] Compensation Actually Paid vs. Total Shareholder Return Compensation Actually Paid vs. Total Shareholder Return [Text Block] Operating losses carry forward, maximum deductibility percentage Operating Losses Carry Forward Maximum Deductibility Percentage Operating losses carry forward, maximum deductibility as a percentage of taxable income. Weighted Average Weighted Average [Member] Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Table] Fair Value, Recurring and Nonrecurring [Table] Lease and Rent Expense Lessee, Leases [Policy Text Block] Entity Central Index Key Entity Central Index Key PEO Name PEO Name Schedule of Minimum Future Payments on Long-Term Debt Schedule of Maturities of Long-Term Debt [Table Text Block] Revenue Revenue Revenues Prior Year End Fair Value of Equity Awards Granted in Any Prior Year that Fail to Meet Applicable Vesting Conditions During Covered Year Prior Year End Fair Value of Equity Awards Granted in Any Prior Year that Fail to Meet Applicable Vesting Conditions During Covered Year [Member] Number of wholly owned subsidiaries Number Of Wholly Owned Subsidiaries Number of wholly owned subsidiaries. Supplemental non-cash information: Supplemental Non Cash Information Related To Leases [Abstract] Supplemental non-cash information related to leases. Outstanding Aggregate Erroneous Compensation Amount Outstanding Aggregate Erroneous Compensation Amount Arrangement Duration Trading Arrangement Duration Schedule of Segment Reporting Information, by Segment [Table] Schedule of Segment Reporting Information, by Segment [Table] Research Funding Payments Research Funding Payments [Member] Research funding payments. ARV-806 ARV-806 [Member] ARV-806 Expected volatility, maximum (percentage) Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Volatility Rate, Maximum Deferred revenue Contract with Customer, Liability, Current Segments [Axis] Segments [Axis] Warrant exercise price (in usd per share) Class of Warrant or Right, Exercise Price of Warrants or Rights Prepaid expenses and other assets Increase (Decrease) in Prepaid Expense and Other Assets Exercise Price Award Exercise Price Entity Filer Category Entity Filer Category Local Phone Number Local Phone Number Additional 402(v) Disclosure Additional 402(v) Disclosure [Text Block] Collaborative Arrangement and Arrangement Other than Collaborative [Domain] Collaborative Arrangement and Arrangement Other than Collaborative [Domain] U.S. Federal statutory tax rate Effective Income Tax Rate Reconciliation, at Federal Statutory Income Tax Rate, Percent Leasehold improvement written-off Property, Plant And Equipment, Writeoff Property, Plant And Equipment, Writeoff Equity Share-Based Payment Arrangement [Text Block] Maturities of marketable securities Proceeds From Maturities Of Marketable Securities Proceeds from maturities of marketable securities. Assets Assets [Abstract] Long term debt Total long-term debt Long-Term Debt, Excluding Current Maturities Underlying Security Market Price Change Underlying Security Market Price Change, Percent Class of Warrant or Right [Domain] Class of Warrant or Right [Domain] Debt Instrument [Axis] Debt Instrument [Axis] Forfeited (in dollars per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Forfeitures, Weighted Average Grant Date Fair Value Marketable Securities and Fair Value Measurements Fair Value Disclosures [Text Block] Deferred income tax assets: Deferred Tax Assets, Net [Abstract] Stockholders' equity: Equity, Attributable to Parent [Abstract] Vesting Date Fair Value of Equity Awards Granted and Vested in Covered Year Vesting Date Fair Value of Equity Awards Granted and Vested in Covered Year [Member] Entity Address, Address Line One Entity Address, Address Line One Entity Address, Address Line Two Entity Address, Address Line Two Share repurchases (Treasury stock) Treasury Stock, Value, Acquired, Cost Method Research and development Total research and development expense Research and Development Expense Accumulated Other Comprehensive Loss (Income) AOCI Attributable to Parent [Member] Interest Rate Debt instrument bearing interest rate Debt Instrument, Interest Rate, Stated Percentage Investment, Name [Axis] Investment, Name [Axis] Operating lease liability Operating Lease, Liability, Noncurrent Entity Voluntary Filers Entity Voluntary Filers Loan forgiveness Debt Instrument Loan Forgiveness Debt Instrument Loan Forgiveness General and administrative and commercial expenses Accrued General And Administrative And Commercial, Current Accrued General And Administrative And Commercial, Current Genentech Genentech Incorporation And F Hoffman La Roche Limited [Member] Genentech, Incorporation. and F. Hoffman-La Roche Limited. Summary Of Significant Accounting Policies [Line Items] Summary Of Significant Accounting Policies [Line Items] Summary of significant accounting policies. Research Collaboration And License Agreements [Line Items] Research Collaboration And License Agreements [Line Items] Research collaboration and license agreements. Fair Value as of Grant Date Award Grant Date Fair Value Property, Plant and Equipment [Abstract] Property, Plant and Equipment [Abstract] Entity Registrant Name Entity Registrant Name Percentage of liquidated damages Percentage Of Liquidated Damages Percentage of liquidated damages. 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